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Comparative gene profiling study: Pak1 deficient human breast cancer cells vs Pak1 wt breast cancer cells

ABSTRACT: To identify differentially regulated genes between wild-type and Pak1 deficient human breast cancer cells, we performed a comparative gene profiling study by using human whole genome arrays. We compared the gene expression profiles of MCF10A.B2 cells (MCF10A cells expressing a chemically activatable form of Her2) stably expressing a Tet inducible shRNA directed against Pak1 gene. All the experiments were performed in duplicate using tumor derived cells from two different tumors per group.

ORGANISM(S): Homo sapiens

SUBMITTER: Luis Arias-Romero

PROVIDER: E-GEOD-71283 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Comparative gene profiling study: Pak1 deficient mouse breast cancer cells vs Pak1 wt breast cancer cells

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Pak1-ATF2 signaling axis induces miR-132 to inhibit hematogenous metastasis

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