Expression analysis of zebrafish liver after exposure in naphthalene

ABSTRACT: Investigation of whole genome gene expression level changes in zebrafish liver under naphthalene treated�high-concentration group and low-concentration group�, compared to the solvent control group revealed that 76 genes and 88 genes were differentially expressed respectively in the fish caged at the low-concentration and high-concentration. KEGG pathway and GO analysis of the differentially expressed genes, showed significant enrichment in several meaningful categories. Healthy 5-month-old adult zebrafish (AB strain) maintenance and chemical exposure to 84μg/L and 840μg/L naphthalene and 0.005% Dimethyl sulfoxide as the solvent control were performed according to published research protocols. Prior to exposure, the fish were acclimatized in 50L aerated fresh water in glass tanks for

ORGANISM(S): Danio rerio

SUBMITTER: Hongshan Chen 

PROVIDER: E-GEOD-74776 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress