Investigating H. Influenzae Species Diversity by Comparative Genomic Hybridization

ABSTRACT: Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single referen

ORGANISM(S): Haemophilus influenzae

SUBMITTER: Q. Sun 

PROVIDER: E-GEOD-8300 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress