Transcription profiling of adipocytes and stromo-vascular fraction from subcutaneous and intraabdominal mouse adipose tissue

ABSTRACT: Obesity is an epidemic health problem worldwide that impacts the risk and prognosis of many diseases. However, not all obese patients have the same risk of developing these disorders. Individuals with peripheral obesity, i.e., fat distributed subcutaneously, are at little or no risk of the common medical complications of obesity, whereas individuals with central obesity, i.e., fat accumulated in visceral depots, are prone to these complications. In the present study, using microaarays gene expression, we have explored the hypothesis that patterns of fat distribution and, perhaps, to some degree, obesity itself may have a developmental genetic origin. Experiment Overall Design: Isolated adipocytes and stromo-vascular fraction (SVF) of subcutaneous and intraabdominal adipose tissue of mice w

ORGANISM(S): Mus musculus

SUBMITTER: Stephane Gesta 

PROVIDER: E-GEOD-8505 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress