Transcription profiling of rat epididymal fat tissues from diet induced obesity model against lean controls

ABSTRACT: Analysis of gene expression profiles of epididymal fat from DIO rats; We applied a comparative functional genomics approach to evaluate diet-induced obese (DIO) rats as an obesity model Experiment Overall Design: Gene expression profiles from DIO and lean rats were generated and compared. A private colony of male Long-Evans rats was set up at Harlan (Harlan-Sprague Dawley, Indianapolis, IN). The animals had been on either a high fat/high sucrose diet (TD95217, Harlan Takled, Madison, WI) or a regular chow (Purina 5008; Ralston-Purina, St. Louis, MO) since weaning. Rats were shipped at 14-weeks of age to our facility and maintained on a 12:12-hour light-dark photoperiod (light on 10:00 PM). They were individually housed throughout the study at ambient temperature, and had free access to

ORGANISM(S): Rattus norvegicus

SUBMITTER: Dan Li 

PROVIDER: E-GEOD-8700 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress