Transcription profiling of Drosophila to investigate mutations increasing life span

ABSTRACT: Mutations Increasing Drosophila melanogaster; Life Span. (Under the direction of Trudy F. C. Mackay.); Better living conditions and advances in medicine have made it possible for; humans to live considerably longer than before. This has uncovered many; health problems associated with age. By identifying genes involved in the; limitation of life span, we may better understand the processes that lead to aging. In model organisms, we can use mutagenesis to discover mutations that; increase life span, and hence infer that the wild-type allele limits life span by some means. We have assessed longevity in a collection of 1332 co-isogenic gene-trap; P-element insertion lines and determined changes in life span of each insert line relative to the corresponding control line. Significant lines were

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Mike Magwire 

PROVIDER: E-GEOD-8775 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress