Transcription profiling of Drosophila isogenic lines at two embryonic time points to identify gene expression variation underlying evolutionary traits

ABSTRACT: Variation in gene expression may underlie many important evolutionary traits. However, it is not known at what stage in organismal development changes in gene expression are most likely to result in changes in phenotype. One widely held belief is that changes in early development are more likely to results in changes in downstream phenotypes. In order to discover how much genetic variation for transcript level is present in natural populations, we studied zygotic gene expression in nine inbred lines of Drosophila melanogaster at two time points in development. We find abundant variation for transcript level both between lines and over time: close to half of all expressed genes show a significant line effect at either time point. We examine the contribution of maternally-loaded genes to

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Matthew Hahn 

PROVIDER: E-GEOD-8892 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress