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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human embyronic kidney cells and mouse L929 cells grown in culture with microspheres

ABSTRACT: To fully understand the effect of microspheres on genes coding for toxic products, signalling molecules, cell stress responses and so forth. Gene expression profiling using a microarray-based technology allows the expression analysis of thousands of genes simultaneously. This method is more informative than traditional studies on single genes, providing information on networks of gene expression changes in a high-throughput manner. In particular, this approach has been used successfully to study the interaction between cells and their polymers supports yielding enormous information concerning the cell-polymer interactions. Thus, this technique offers a significant contribution towards fully understanding the nature of beadfected cells and the possible transcriptomic alterations that may occur.

ORGANISM(S): Mus musculus

SUBMITTER: Salvatore Pernagallo

PROVIDER: E-MEXP-1845 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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