Transcription profiling of mouse thymus glandwfrom normal and ollagen induced arthritis animals

ABSTRACT: DBA/1J and DBA-2/J mice (12-14 weeks old) weighing 18�22 g were housed in temperature-controlled rooms (22�25�C) in the animal facility of the School of Medicine of Ribeir�o Preto, University of S�o Paulo, S�o Paulo, Brazil, and received water and food ad libitum. DBA/1J and DBA-2/J male mice were used in type II collagen immunizations. For CIA, at day zero, DBA/1J males were intradermally injected at the base of the tail with 200 �g of bovine type II collagen (CII) (Sigma) in 100�l of 0.05 M acetic acid emulsified with equal volume of complete Freund�s adjuvant (Chondrex, Redmond, WA). On day 21, a second injection of CII (200 �g in acetic acid) was given intraperitoneally (i.p). DBA/2J males were also immunized with CII and served as controls. A caliper was used to de

ORGANISM(S): Mus musculus

DISEASE(S): collagen induced arthritis

SUBMITTER: Geraldo Passos 

PROVIDER: E-MEXP-2338 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress