Transcription profiling by array of rat macrophages from WKY/NCrl and LEW/Crl strains to determine susceptibility to glomerulonephritis

ABSTRACT: The Wistar-Kyoto (WKY) rat shows marked susceptibility to crescentic glomerulonephritis, while Lewis rats are resistant. Glomerular injury and crescent formation are macrophage-dependent. The aim of this study is to use gene expression profiling to identify genetic factors that determine macrophage activation and render WKY rats susceptibile to glomerulonephritis.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Klio Maratou 

PROVIDER: E-MEXP-2624 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress