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Unknown,Transcriptomics,Genomics,Proteomics

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Long term radiation effects in A549 cells - PML knock down and carbon ion vs. photon irradiation

ABSTRACT: The aim of our study is to investigate the effects of carbon ion and photon irradiation on A549 tumor cells and analyse how these effects are altered by PML knockdown. Therefore we created PML knockdown A549 cells (shPML) and irradiated them with either 2Gy carbon ion or 6Gy Photon (bioequivalent doses). 4 days after irradiation microarray analysis was performed. All experiments were performed in 3 biological replicates and control groups were transduced with an empty vector.

ORGANISM(S): Homo sapiens

SUBMITTER: Christian Schwager

PROVIDER: E-MEXP-3965 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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