Time Series gene expression profiling of Lethal Giant Larvae tumours in developing wings of Drosophila larvae

ABSTRACT: Cancer is a complex phenomenon involving multiple cellular pathways and processes in various combinations. As a genetic system, Drosophila has contributed much to our understanding of processes that initiate tumorigenesis. However, these are still disparate threads of information and a comprehensive understanding of how these various events and processes come together to bring about tumorous transformation is still wanting. The present study is an attempt to create a comprehensive picture of the dynamic process of epithelial tumour development in imaginal discs using lgl mutants as a model of neoplastic transformation. Experimental Procedure: The experiments were carried out in isogenized w-; lgl4. FRT40A/CyO. Actin –GFP (E Gateff and Schneiderman 1974). Fairly homogenous cultures of

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Subhabrata Pal 

PROVIDER: E-MTAB-10059 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress