Transcription profiling by array of fibroblasts from eight individuals to evaluate variability in the establishment of induced pluripotent stem cell lines and to develop future cellular models of disease.

ABSTRACT: Fibroblasts from eight individuals were chosen to evaluate variability in the establishment of iPSC lines and to develop future cellular models of disease. From the eight patients four were healthy controls (Cont) and four were schizophrenic (Sz). All the patients were males with ages ranging from 21-51 and both groups (Cont vs Sz), were age matched. Primary fibroblasts were reprogrammed using lentivirus expressing Oct4, Sox2, Klf4 and cMyc

ORGANISM(S): Homo sapiens

SUBMITTER: Nicholas Matigian 

PROVIDER: E-MTAB-1040 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress