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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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NanoString profiling of host response in healthy volunteers vaccinated with ARCT-021 self-amplifying mRNA vaccine or placebo

ABSTRACT: Transcriptomic profiling was conducted on whole blood collected from study participants (NCT04480957). A total of 106 healthy participants were randomized into single and two-injection cohorts. Gene transcript levels were determined at baseline (pre-dose 1), day 2, 3, and 8 for all vaccinees. In addition, gene expression was profiled at day 29 (pre-dose 2), 30 and 36 among vaccinees in the two-injection cohort. Whole blood was collected in Tempus Blood RNA tubes, and RNA was extracted from whole blood using the Tempus Spin RNA Isolation Kit.

ORGANISM(S): Homo sapiens

SUBMITTER: Eugenia Ong

PROVIDER: E-MTAB-11315 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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