Project description:To investigate the effect on chromatin accessibility with reduced ERBB2 signalling in oesophageal adenocarcinoma, we performed ATAC-seq in OE19 cells treated with either siNT or siERBB2.

2020-09-30 | E-MTAB-8576 | biostudies-arrayexpress

ATAC-seq of human oesophageal adenocarcinoma OE19 cell line treated with lapatinib

Project description:To investigate changes to chromatin accessibility associated with resistance to lapatinib, we performed ATAC-seq on OE19 cells treated with 500 nM lapatinib for 1, 7 and 35 days and vehicle control (DMSO) for 1 day.

2022-09-26 | E-MTAB-10302 | biostudies-arrayexpress

ATAC-seq of Het1A cells with overexpression of HNF4A or GATA6

Project description:To determine the ability of HNF4A and GATA6 to drive open chromatin formation, either HNF4A or GATA6 were overexpressed in normal oesophageal Het1A cells and ATAC-seq was performed.

2019-02-04 | E-MTAB-6931 | biostudies-arrayexpress

ATAC-seq of oesophageal adenocarcinoma patient samples

Project description:Open chromatin profiling (ATAC-seq) of human oesophageal adenocarcinoma patient samples.

2020-09-30 | E-MTAB-8447 | biostudies-arrayexpress

ATAC-seq of liver of a Holstein Friesian infant male.

Project description:We performed the assay for transposase-accessible chromatin using sequencing (ATAC-seq) on a liver sample collected from one Holstein Friesian healthy male at one month of age to profile open chromatin regions genome-wide to identify putative regulatory elements related to phenotype of interest.

2021-07-09 | E-MTAB-9872 | biostudies-arrayexpress

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