Profiling by array of human Glioblastoma multiforme (GBM) tumor samples to asses the intra-tumoral heterogeneity in genomic copy number aberrations

ABSTRACT: Glioblastoma multiforme (GBM) is a highly heterogeneous disease that shows an wide range of genetic abnormalities in comparison to other astrocytic tumors. We have extracted between 4 and 8 tumor subsamples from different areas of the malignant tissue that were at least 1cm apart. Our aim to asses the intra-tumoral heterogeneity by comparing copy number aberrations in different tumor areas to uncover important dynamics underlying GBM progression.

ORGANISM(S): Homo sapiens

SUBMITTER: Andrea Sottoriva 

PROVIDER: E-MTAB-1215 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress