Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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A systems biology view of responses to lignin biosynthesis perturbations in Arabidopsis


ABSTRACT: Inflorescence stems of 20 Arabidopsis thaliana mutants, each mutated in a single gene of the lignin biosynthetic pathway (PAL1 , PAL2, C4H, 4CL1, 4CL2, CCoAOMT1, CCR1, F5H1, COMT and CAD6, two mutant alleles each) were analyzed by microarrays.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Veronique Storme 

PROVIDER: E-MTAB-1284 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A systems biology view of responses to lignin biosynthesis perturbations in Arabidopsis.

Vanholme Ruben R   Storme Véronique V   Vanholme Bartel B   Sundin Lisa L   Christensen Jørgen Holst JH   Goeminne Geert G   Halpin Claire C   Rohde Antje A   Morreel Kris K   Boerjan Wout W  

The Plant cell 20120925 9


Lignin engineering is an attractive strategy to improve lignocellulosic biomass quality for processing to biofuels and other bio-based products. However, lignin engineering also results in profound metabolic consequences in the plant. We used a systems biology approach to study the plant's response to lignin perturbations. To this end, inflorescence stems of 20 Arabidopsis thaliana mutants, each mutated in a single gene of the lignin biosynthetic pathway (phenylalanine ammonia-lyase1 [PAL1], PAL  ...[more]

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