Dataset Information

A proteomic view of butterfly morphogenesis

ABSTRACT: Insect metamorphosis is one of the most fascinating developmental processes in the natural world. Complete metamorphosis requires the breakdown and re-organization of larval tissues, and the coordinated construction and development of adult structures. The molecular events that achieve this transformation are however incompletely understood, and there is in particular a shortage of data describing changes in protein abundance that occur during the metamorphic journey. Here we provide data from a proteomic analysis of consecutive developmental stages of a laboratory butterfly as it develops from a caterpillar into an adult via pupation. This provides a dynamic reference dataset representing 2749 detected proteins. Statistical analysis identified 90 proteins changing significantly in abundance during metamorphosis, and functional interpretation highlights cuticle formation, apoptosis and autophagy during the pupal stages, and the up-regulation of respiration and energy metabolism upon emergence of the fully formed adult. A search for peptide phosphorylation modifications in the data identified three proteins with roles in muscle function suggesting developmental stage-dependent phosphorylation events.

INSTRUMENT(S):

ORGANISM(S): Bicyclus Anynana

SUBMITTER: Vaishnavi Ravikumar

LAB HEAD: Marjorie Fournier

PROVIDER: PXD065563 | Pride | 2026-01-05

REPOSITORIES: pride

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			Action	DRS
	PD_search_files.rar	Other
	QEX03_VR_240530_JK_2P10_399.raw	Raw
	QEX03_VR_240530_JK_2P13_401.raw	Raw
	QEX03_VR_240530_JK_2P14_403.raw	Raw
	QEX03_VR_240530_JK_4P10_395.raw	Raw

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A Proteomic View of Butterfly Metamorphosis.

Hesketh Andrew A Kadiwala Juned J Ravikumar Vaishnavi V Garizo Ana Rita AR Beldade Patrícia P Fournier Marjorie M Shakur Rameen R

Proteomes 20251218 4

<h4>Background</h4>Insect metamorphosis is one of the most fascinating developmental processes in the natural world. Complete metamorphosis requires the breakdown and reorganisation of larval tissues and the coordinated construction and development of adult structures. The molecular events that achieve this transformation are, however, incompletely understood, and there is a particular shortage of data describing changes in protein abundance that occur during the process.<h4>Methods</h4>Here, us ...[more]

PMID: 41441339

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