RNA-seq of human AML patient samples with complex karyotype

ABSTRACT: Acute myeloid leukemia with complex karyotype (CK-AML) is characterized by three or more chromosomal aberrations, and comprises 10–12% of AML patients. It is associated with complex chromosomal rearrangements, intra-tumor heterogeneity, therapy resistance and poor overall survival. We aimed to transcriptionally characterize CK-AML by performing RNA sequencing on blasts from 4 CK-AML patient samples.

INSTRUMENT(S): NextSeq 550

ORGANISM(S): Homo sapiens

SUBMITTER: Aino-Maija Leppä 

PROVIDER: E-MTAB-14420 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress