Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq data of acute leukemias of ambiguous lineage (ALAL)


ABSTRACT: We generated RNA-seq data of 30 cases of acute leukemia of ambiguous lineage (ALAL), including both bilineal and biphenotypic patients, in order to develop methods to improve the diagnosis of this disease. First, we used an in-house pipeline to comprehensively detect genetic lesions in RNA-sequencing data. Second, we generated a machine learning (ML) classifier trained on compared ALAL gene expression profiles (GEPs) with representative AML (n=145), B-ALL (n=223) and T-ALL (n=85) cases.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Roger Mulet-Lazaro 

PROVIDER: E-MTAB-15145 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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