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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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K562 cells treated with 10ng/ml TNFα, profiled with ChronoSeq for 12 samples barcoded with unique Time-Tags

ABSTRACT: Both Live-cell imaging studies and scRNA-seq studies have shown multiple heterogeneous responses to the same stimulus in the same cells. Therefore as a first application we investigated if ChronoSeq could also reveal the heterogeneity in stimulus response; we applied ChronoSeq to profile inflammatory responses in K562 cells stimulated with TNF-α, to capture the rapid NF-κB signaling cascade. 10 minute interval between samples including a 1 minute sampling duration.

INSTRUMENT(S): Illumina NovaSeq X, ChronoSeq

ORGANISM(S): Homo sapiens

SUBMITTER: Kanishk Asthana

PROVIDER: E-MTAB-15894 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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