RNA-Seq profiling of S. Cerevisiae WT BY4741 cells and MOH1-knockout mutants of BY4741 cells (moh1∆) after growth on YPD-Agar for 40 hours

ABSTRACT: The Yippee-like (YPEL) proteins are a conserved eukaryotic gene family implicated in proliferation, senescence, and stress adaptation. In humans, five paralogs (YPEL1–YPEL5) are widely expressed and encode proteins with high sequence similarity, but the molecular basis of their functions remains poorly defined. Functional redundancy among YPEL paralogs complicates the clarification of their individual roles. The budding yeast Saccharomyces cerevisiae has a single ortholog, MOH1, which is involved in survival and stress responses and can be functionally complemented by human YPELs. However, the cellular function of MOH1 has yet to be elucidated. Here, we investigated the function of MOH1 in S. cerevisiae. Deletion of MOH1 (moh1Δ) conferred sensitivity to sodium azide and sulfuric acid but i

INSTRUMENT(S): DNBSEQ-G400

ORGANISM(S): Saccharomyces cerevisiae S288c

SUBMITTER: Çağla Ece Olgun 

PROVIDER: E-MTAB-16090 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress