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MEX3A Promotes Nasopharyngeal Carcinoma Progression by Regulating Alternative Splicing of Cell Cycle-Related Genes

ABSTRACT: Based on public databases, transcriptome data from NPC (GSE68799) and head and neck cancer (TCGA, HNSC) patients were downloaded, and the differentially expressed RBP-MEX3A was identified through bioinformatic analysis. An MEX3A overexpression model was subsequently established in C666-1 cells. Cell proliferation was assessed using the CCK-8 assay, and apoptosis was analyzed by flow cytometry. Transcriptome sequencing was performed to systematically identify differentially expressed genes (DEGs) and alternative splicing (AS) events induced by MEX3A overexpression.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: xiao Han

PROVIDER: E-MTAB-16434 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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