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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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ScRNA-seq of control and IL-1RAcP knockout across Candida infection timecourse

ABSTRACT: Single-cell RNA sequencing was performed on murine oral tissue to characterise immune responses during Candida albicans infection. Control and IL-1RAcP knockout mice were analysed across a time course comprising naïve (uninfected), day 1, and day 2 post-infection samples. The dataset captures genotype-dependent differences in epithelial and immune cell populations and their transcriptional responses to infection. This study enables analysis of cell-type composition, activation states, and gene expression dynamics across infection and between genotypes.

INSTRUMENT(S): NextSeq 2000

ORGANISM(S): Mus musculus

SUBMITTER: James Griffiths

PROVIDER: E-MTAB-16924 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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