Transcription profiling of Salmonella enterica serovar Typhimurium definitive phage type 104 (DT104) isolates

ABSTRACT: Salmonella enterica serovar Typhimurium (S. Typhimurium) definitive phage type 104 (DT104) has caused significant morbidity and mortality in humans and animals for almost three decades. We have completed the full DNA sequence of one DT104 strain, NCTC13348 and show that the main differences between the genome of this isolate and the previously sequenced S. Typhimurium LT2 lie in integrated prophage elements and the Salmonella Genomic Island 1 encoding antibiotic resistance genes. Thirteen isolates of S. Typhimurium DT104 with different pulsed field gel electrophoresis (PFGE) profiles were analyzed by multi locus sequence typing (MLST), plasmid profiling, hybridization to a Pan-Salmonella DNA microarray and prophage-based multiplex PCR. All the isolates belonged to a single MLST type ST19.

ORGANISM(S): Salmonella enterica

SUBMITTER: Maria Fookes 

PROVIDER: E-MTAB-20 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress