Transcription profiling by array Saccharomyces cerevisiae after GGTI-298 treatment.

ABSTRACT: Global gene expression on yeast cells was determined after a drug induced inhibition of GGTase I by treating yeast cells with GGTI298 (Cabiochem). GGTI298 treated cells were grown for 2 generations to exponential phase in parallel with untreated cells. RNA was extracted, subsequently cDNAs were labelled and hybridized on UHN Y6.4k4 arrays. Replicates with dye-swap of the experiments were generated. Results enabled us to identify the genome-wide effects after drug-induced GGTase I inhibition

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Giampiero Porcu 

PROVIDER: E-MTAB-217 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress