Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of yeast grwon in high glucose medium and shifted to low glucose medium


ABSTRACT: Time series expression profile of yeast cells grown at high glucose and shifted to low glucose containing medium. Lowess normalized data in raw data files.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Marian Groot Koerkamp 

PROVIDER: E-MTAB-22 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Cooperative action of NC2 and Mot1p to regulate TATA-binding protein function across the genome.

van Werven Folkert J FJ   van Bakel Harm H   van Teeffelen Hetty A A M HA   Altelaar A F Maarten AF   Koerkamp Marian Groot MG   Heck Albert J R AJ   Holstege Frank C P FC   Timmers H Th Marc HT  

Genes & development 20080814 17


Promoter recognition by TATA-binding protein (TBP) is an essential step in the initiation of RNA polymerase II (pol II) mediated transcription. Genetic and biochemical studies in yeast have shown that Mot1p and NC2 play important roles in inhibiting TBP activity. To understand how TBP activity is regulated in a genome-wide manner, we profiled the binding of TBP, NC2, Mot1p, TFIID, SAGA, and pol II across the yeast genome using chromatin immunoprecipitation (ChIP)-chip for cells in exponential gr  ...[more]

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