Transcription profiling during differentiation of the neural tube in HH stage 10 chick embryos

ABSTRACT: The spinal cord is generated progressively as cells leave the caudal region of the elongating body axis such that the temporal steps of neural differentiation become spatially separated along the head to tail axis. At key stages, it is therefore possible to isolate near-adjacent cell populations from the same embryo in distinct differentiation states. Cells in the caudal lateral epiblast adjacent to the primitive streak (also known as the stem zone, SZ, in the chick) express both early neural and mesodermal genes. Other cells in the stem zone will gastrulate to form the paraxial mesoderm or remain in the epiblast cell sheet and become neural progenitors. These latter cells form a new region called the preneural tube (PNT), which is flanked by unsegmented presomitic mesoderm and represents

ORGANISM(S): Gallus gallus

SUBMITTER: Nicholas Schurch 

PROVIDER: E-MTAB-2734 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress