Unknown,Transcriptomics,Genomics,Proteomics

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Expression profiling of ncRNAs with custom microarray of CaV 1.3 knockout mice compared to wild type mice

ABSTRACT: For screening mouse models for CNS diseases for changes in ncRNA expression, we first investigated two models with impaired voltage-gated Ca2+ channel activity, i.e. the lethargic mutant of the auxiliary calcium channel β4 subunit (Cacnb4lh; (Burgess et al. 1997)) and knockout mice for the L-type calcium channel CaV1.3 (Platzer et al. 2000), which have been implicated in a variety of neurological disorders such as psychiatric disorders (Cacnb4) or Parkinsons disease (Cav1.3).

ORGANISM(S): Mus musculus

SUBMITTER: Simon Schafferer

PROVIDER: E-MTAB-2742 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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