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A novel miRNA fingerprint inversely associated with breast cancer progression in SKBR3 cells challenged with all-trans retinoic acid and lapatinib

ABSTRACT: In SKBR3 cells, simultaneous targeting of RARM-kM-1 with all-trans retinoic acid (ATRA) and HER2 with lapatinib results in synergistic anti-tumor responses. SKBR3 cells were treated with vehicle (DMSO), lapatinib (100 nM), ATRA (100 nM) or lapatinib+ATRA for 36 hours and miRNA expression profile was determined by one-color Agilent microarray experiments.

ORGANISM(S): Homo sapiens

SUBMITTER: Maddalena Fratelli

PROVIDER: E-MTAB-3097 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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