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Human primary macrophages infected with dengue virus serotype 2, strain 16681, and antibody-dependent enhancement of infection

ABSTRACT: Human primary monocytes were differentiated for 6days in the presence of M-CSF. The resulting macrophages were infected with dengue virus serotype 2, strain 16681 under the following conditions: Mock, Multiplicity of infection (MOI) 1 without antibodies, MOI 1 with 40ng/mL of irrelevant human antibody, MOI 1 with infection enhancing antibody (40ng/mL of a human monoclonal antibody against dengue), and either MOI 5 or MOI 2.5. Total cell RNA was isolated at 2h post infection or 24h post infection.

INSTRUMENT(S): Illumina BeadArray reader

ORGANISM(S): Homo sapiens

SUBMITTER: Jacky Flipse

PROVIDER: E-MTAB-3138 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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