The identification of positive chicken factors for influenza polymerase activity

ABSTRACT: Using a chicken-hamster radiation hybrid panel (ChickRH6), we have mapped chicken chromosome(s) that contain possible factor(s) that permit avian polymerase activity, by increasing polymerase activity. We identified four hybrid clones permissive for polymerase activity. Activity was lost following 12 passages respectively in only one of the positive clones. Expression from the four positive radiation hybrid clones at passages 1, and 12 was measured and compared to expression of the hamster recipient line and 17 negative (for polymerase activity) clones.

ORGANISM(S): Cricetulus griseus

SUBMITTER: Efstathios Giotis 

PROVIDER: E-MTAB-3643 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress