Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

51 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Aging effect on interfollicular epidermis (paw skin)

ABSTRACT: We have employed whole genome microarray expression profiling to identify genes with the potential to distinguish young and aged interfollicular epidermis. Gene expression of paw whole skin samples from 4 young (6 week-old) and 4 aged (102 week-old) C57BL6 mice was analyzed.

ORGANISM(S): Mus musculus

SUBMITTER: Ken Natsuga

PROVIDER: E-MTAB-4916 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Shared Molecules

Only show the datasets with similarity scores above: 0.5

Threshold

0.5

Similar Datasets

E-MTAB-8922

Project description:RNA from young and aged mouse hematopoietic stem cells

2020-04-03 | E-MTAB-8922 | ExpressionAtlas

Transcription profiling by array of mouse hind paws after receiving KRN T cells from K/BxN mice

Project description:K/BxN mice were generated by crossing KRN males with NOD females, and it was these mice that served as the source for the T cells adoptively transferred. Male B6.TCR.Ca-/-H-2b/g7 (recipient) mice age 10-14 weeks old were used in this model and are the source of the paw tissue profiled in this study.

2010-04-23 | E-TABM-966 | biostudies-arrayexpress

oocyte miRNA profiling by array

Project description:This study compares miRNA expression profiles in mouse oocytes as young oocytes vs aged oocytes, and growing oocytes vs small oocytes from primordial follicles. Oocytes were derived from the ovary of young (6-8 week-old) C57BL/6 mice and aged (41-43 week-old) mice and pooled according to whether they were 20 to 50 um or 60 to 80 um in diameter. Of oocytes with the diameter of more than 60um, oocyte from young mice are called ‘young oocytes’ and those from aged mice near the end of their reproductive life span are called ‘aged oocytes’ to analyze the miRNA profiling associated with aging. They were also each called ‘small oocytes’ or ‘large oocytes’ from the size of 60um so as to investigate miRNA profiling associated with growing. Total RNA from oocytes was isolated using mirVana miRNA Isolation Kit (Applied Biosystems). MiRNA expression was profiled using Agilent's Mouse miRNA Microarray Kit (G4472A) annotated against the Sanger miRBASE 10.1 database of miRNAs. This miRNA microarray was provided by Agilent Technologies (Santa Clara, CA). Each sample was run in duplicate.

2012-09-04 | E-GEOD-17966 | biostudies-arrayexpress

E-GEOD-854

Project description:Transcription profiling by array of hippocampus from young, middle-aged, and old rats

2014-07-03 | E-GEOD-854 | ExpressionAtlas

RNA-sequencing of cultured young (2-3mos) and aged (20-22mos) mouse brain ILC2

Project description:We investigated how aging impacts the ILC2 population in the brain. Through RNA-sequencing of 2-week culture of sorted brain ILC2 from young and aged mice,we identified differential gene expressions regarding cellular exhaustion and self-renewal between young and aged brain ILC2.

2020-01-21 | GSE129992 | GEO

Gene expression profiles of young and aged endothelial cells isolated from the murine liver

Project description:To investigate the effect of aging on liver endothelial cells, we performed RNA sequencing of liver endothelial cells isolated from young (10-week-old) and aged (127-136 week-old) C57BL/6J mice.

2023-08-13 | GSE233052 | GEO

MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation

Project description:We compared the aorta of 6-weeks-old mice (young) with 18-months-old mice (old). Using the publicly available tools Sylamer and DIANA-mirExTra, we identified an enrichment for miR-29 binding sites in the 3'UTR of genes downregulated in the aged aortas. We subsequently showed that inhibition of miR-29 in aged mice prevented dilation of the aorta. aortas of 6 week old and 18 month old mice

2011-10-13 | E-GEOD-32937 | biostudies-arrayexpress

Age-dependent Response of Isolated Male Germ Cells to Oxidative Stress

Project description:Male germ cells from young and aged Rats were Isolated and cultured and then treated with pro-oxidant SIN-1 and antioxidant EUK134 Study of the response of isolated male germ cells from young and aged Brown Norway Rats to oxidative stress. Treatment of Isolated and cultured germ cells with pro-oxidant and antioxidant.

2015-04-30 | E-GEOD-66976 | biostudies-arrayexpress

MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation

Project description:To identify microRNAs which differentially expressed in the BMSCs of aged and young mice and and investigate its influences on BMSCs differentiation with ageing. The microRNAs expressions of BMSCs from 3 aged mice and 3 young mice were measured.

2014-04-29 | E-GEOD-57127 | biostudies-arrayexpress

scRNA-seq of young and aged lungs following influenza A virus infection

Project description:Aging is known to alter the host repsonse to influenza infection. Here, we use single-cell RNA sequencing (scRNA-seq) to identify cellular changes in the lungs of young (16-week-old) and aged (80-week-old) mice following influenza infection.

2023-09-05 | GSE202325 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data