DNA methylation array of human purified intestinal epithelial samples and organoids from paediatric and foetal small and large intestine

ABSTRACT: Human intestinal epithelial organoids (IEO) culture models are rapidly emerging as novel experimental tools to investigate fundamental aspects of intestinal epithelial (patho)physiology. Cellular source and culture protocols vary between different IEO models and reliable markers for their characterization/validation are currently limited. DNA methylation has been demonstrated to play a key role in regulating gene expression and cellular function. This epigenetic mark is comparably stable and has been shown to reflect cellular identity such as tissue origin, developmental stage and age. Our genome wide DNA methylation datasets of purified human epithelium represent a unique resource, which can be used by other researchers to validate their model systems We provide the following datasets of

ORGANISM(S): Homo sapiens

SUBMITTER: Judith Kraiczy 

PROVIDER: E-MTAB-4957 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress