Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter


ABSTRACT: To initially determine changes on the transcriptome level that might account for the phenotypic observations in an unbiased fashion, we performed large-scale mRNA expression profiling 8 weeks after treatment with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter. Mice were subjected to 16 h fasting or a 16 h fasting + 6 h refeeding cycle before termination of the experiment. All 8 AAV-injected experimental groups as NC and GAbpα knockdown samples for the different conditions (wt or db/db; fasting or refeeding) were included.

ORGANISM(S): Mus musculus

SUBMITTER: Juan Higareda-Almaraz 

PROVIDER: E-MTAB-5775 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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