Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling array of human glioblastoma cell line U87MG comparing control cells (U87RNAi) with U87shLAPTM5 knockdown cells

ABSTRACT: After performing an in-vivo screening with U87 glioblastoma cells transduced with a knockdown library several genes could be identified. LAPTM5 which was one of the candidates was further evaluated. Single knockdown of LAPTM5 in U87MG conferred a pro-invasive phenotype in-vitro and in-vivo. To decipher the underlying pathways U87MG control cells (U87RNAi) and U87shLAPTM5 were analyzed after in-vitro culture by a transcription profiling Array.

ORGANISM(S): Homo sapiens

SUBMITTER: Dieter Lemke

PROVIDER: E-MTAB-6316 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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