Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of E. Coli degradosome mutants and their parental strains to analyse comparative transcript abundance


ABSTRACT: Comparative transcript abundance in E. Coli degradosome mutants and their parental strains.

ORGANISM(S): Escherichia coli

SUBMITTER: Janos Demeter 

PROVIDER: E-SMDB-2680 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications

Global analysis of Escherichia coli RNA degradosome function using DNA microarrays.

Bernstein Jonathan A JA   Lin Pei-Hsun PH   Cohen Stanley N SN   Lin-Chao Sue S  

Proceedings of the National Academy of Sciences of the United States of America 20040223 9


RNase E, an essential endoribonuclease of Escherichia coli, interacts through its C-terminal region with multiple other proteins to form a complex termed the RNA degradosome. To investigate the degradosome's proposed role as an RNA decay machine, we used DNA microarrays to globally assess alterations in the steady-state abundance and decay of 4,289 E. coli mRNAs at single-gene resolution in bacteria carrying mutations in the degradosome constituents RNase E, polynucleotide phosphorylase, RhlB he  ...[more]

Similar Datasets

2006-01-06 | GSE3977 | GEO
2006-01-05 | E-GEOD-3977 | biostudies-arrayexpress
2006-01-06 | GSE3978 | GEO
2006-01-05 | E-GEOD-3978 | biostudies-arrayexpress
2005-11-01 | E-SMDB-2681 | biostudies-arrayexpress
2006-03-08 | GSE4394 | GEO
2006-03-07 | E-GEOD-4394 | biostudies-arrayexpress
2019-06-01 | GSE100022 | GEO
| S-EPMC3709862 | biostudies-literature
2019-04-01 | PXD012662 | Pride