Transcription profiling of rat liver and kidney samples performed in 16 different institutions to determine study factors which are key sources of variability. Raw files available as additional archives.

ABSTRACT: BACKGROUND: The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and technical factors. Meta-analysis of microarray data from untreated or vehicle-treated animals within the control arm of toxicogenomics studies could yield useful information on baseline fluctuations in gene expression, although control animal data has not been available on a scale and in a form best served for data-mining. RESULTS: A dataset of control animal microarray expression data was assembled by a working group of the Health and Environmental Sciences Institute's Technical Committee on the Application of Genomics in Mechanism Based Risk Assessmen

ORGANISM(S): Rattus norvegicus

SUBMITTER: ILSI HESI 

PROVIDER: E-TOXM-39 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress