A retrospective cohort study of geographic differences in the semen of 1,012 sperm donors in China.
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ABSTRACT: Background
Male reproductive health has become a serious public health concern, and semen quality is essential to male reproduction. We aimed to investigate geographical differences in the semen quality of sperm donors from northern and southern China by enrolling donors across the country.Methods
A total of 1,012 sperm donors were enrolled in this study between 2015 and 2019. Donors were first divided into two parts based on their birthplace according to the "Qinling-Huaihe" line, and secondly, by their residential latitude. Finally, donors were re-classified into two groups (typically north and south) which contained 667 samples.Results
Statistically significant differences in sperm concentration were observed among men from different latitudes in China (P=0.04). The sperm concentrations of males from 18° to 27° north latitude were significantly lower than those from 36° to 45° and 45° to 54° [median 131, 134, and 146, respectively, P=0.021 (18° to 27° vs. 36° to 45°) and P=0.01 (18° to 27° vs. 45° to 54°)].Conclusion
We hypothesize environmental pollution and mental stress due to the increased population size may be the main factors underlying differences in the sperm quality of men in northern and southern China.
SUBMITTER: Zhao QC
PROVIDER: S-EPMC10006001 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Publications
A retrospective cohort study of geographic differences in the semen of 1,012 sperm donors in China.
Zhao Qian-Cheng QC Zhang Zhe Z Zhao Lian-Ming LM Deng Zhen-Feng ZF Gao Jiang-Man JM Zhang Hong-Liang HL Lin Hao-Cheng HC Liu De-Feng DF Mao Jia-Ming JM Zhang Hai-Tao HT Chen Yu-Long YL Tang Wen-Hao WH Jiang Hui H
Translational andrology and urology 20230207 2
<h4>Background</h4>Male reproductive health has become a serious public health concern, and semen quality is essential to male reproduction. We aimed to investigate geographical differences in the semen quality of sperm donors from northern and southern China by enrolling donors across the country.<h4>Methods</h4>A total of 1,012 sperm donors were enrolled in this study between 2015 and 2019. Donors were first divided into two parts based on their birthplace according to the "Qinling-Huaihe" lin ...[more]
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