Predominance of Severe Plasma Leakage in Pediatric Patients With Severe Dengue in Puerto Rico.

ABSTRACT:

Background

We evaluated clinical and laboratory findings among patients with nonsevere or severe dengue in Puerto Rico to examine whether clinical manifestations vary by age.

Methods

During 2012-2014, we enrolled patients who arrived at the emergency department with fever or history of fever within 7 days of presentation. Serum samples were tested for dengue virus (DENV) by reverse transcriptase-polymerase chain reaction (RT-PCR) and IgM enzyme-linked immunosorbent assay (ELISA). Severe dengue was defined as severe plasma leakage or shock, severe bleeding, or organ involvement at presentation, during hospitalization, or follow-up.

Results

Of 1089 dengue patients identified, 281 (26%) were severe. Compared to those with nonsevere dengue, patients with severe dengue wer

SUBMITTER: Paz-Bailey G 

PROVIDER: S-EPMC10015274 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature