Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence: A Prospective Cohort Study.

ABSTRACT:

Background

Residual shunt is observed in up to 25% of patients after patent foramen ovale (PFO) closure, but its long-term influence on stroke recurrence currently is unknown.

Objective

To investigate the association of residual shunt after PFO closure with the incidence of recurrent stroke and transient ischemic attack (TIA).

Design

Prospective cohort study comparing stroke or TIA recurrence in patients with and without residual shunt after PFO closure.

Setting

Single hospital center.

Participants

1078 consecutive patients (mean age, 49.3 years) with PFO-attributable cryptogenic stroke who were undergoing percutaneous PFO closure were followed for up to 11 years.

Measurements

Residual shunt was evaluated by transthoracic echocardiography with sal

SUBMITTER: Deng W 

PROVIDER: S-EPMC10021023 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature