Dysphagia and shortness-of-breath as markers for treatment failure and survival in oropharyngeal cancer after radiation.

ABSTRACT:

Background

Post-treatment symptoms are a focal point of follow-up visits for head and neck cancer patients. While symptoms such as dysphagia and shortness-of-breath early after treatment may motivate additional work up, their precise association with disease control and survival outcomes is not well established.

Methods

This prospective data cohort study of 470 oropharyngeal cancer patients analyzed patient-reported swallowing, choking and shortness-of-breath symptoms at 3-to-6 months following radiotherapy to evaluate their association with overall survival and disease control. Associations between the presence of moderate-to-severe swallowing, choking and mild-to-severe shortness-of-breath and treatment outcomes were analyzed via Cox regression and Kaplan-Meier. The main o

SUBMITTER: Wang JH 

PROVIDER: S-EPMC10023381 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature