Parabens and Menopause-Related Health Outcomes in Midlife Women: A Pilot Study.

ABSTRACT: Background: Parabens are antimicrobial agents prevalently found in daily-use products that can interfere with the endocrine and reproductive systems. In this study, we examined the cross-sectional associations of parabens with hot flashes, hormone concentrations, and ovarian volume in a subsample of 101 nonsmoking, non-Hispanic 45- to 54-year-old women from the Midlife Women's Health Study. Materials and Methods: Women self-reported their hot flash history and underwent a transvaginal ultrasound to measure ovarian volume. Participants provided blood for quantification of serum hormones (by enzyme-linked immunosorbent assay or radioimmunoassay) and urine samples for measurements of urinary paraben biomarker levels (by high-performance liquid chromatography negati

SUBMITTER: Pacyga DC 

PROVIDER: S-EPMC10024061 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature