Oil-based or saline contrast for sono-hysterosalpingography in infertile women: a pilot randomized controlled double blind trial.

ABSTRACT:

Objective

To determine the feasibility, safety, and outcomes of an oil-based, iodinated contrast using office-based, ultrasound-imaged hysterosalpingography in women with infertility.

Design

Randomized Controlled Double Blind Clinical Trial.

Setting

Academic health center.

Interventions

Tubal flushing with oil-based contrast medium (Lipiodol UF) versus saline.

Main outcome measures

Ongoing pregnancy rate, pain, quality of life, and thyroid function.

Results

Forty-eight patients (24 in each group) were analyzed. The groups were well-matched at baseline. Ongoing pregnancy was noted in 17% (4/24) of the oil-contrast group versus 37% (9/24) in the saline group. Saline group patients more frequently initiated infertility therapy in the six-month follow

SUBMITTER: Legro RS 

PROVIDER: S-EPMC10028425 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature