Nonalcoholic fatty liver disease in adolescents with phenylketonuria.

ABSTRACT:

Objective

This study aimed to investigate non-alcoholic fatty liver disease (NAFLD) occurrence and factors associated with the disease in phenylketonuria (PKU) patients undergoing exclusive dietary treatment.

Method

This cross-sectional study included 101 adolescents 10 to < 20 years of age with PKU, who were undergoing exclusive dietary treatment and monitored since early diagnosis at a single reference service. Anthropometric and biochemical assessments were performed and food intake was documented, and an ultrasound diagnosis of NAFLD was established. Data were evaluated using the Student's t-test for continuous variables, the chi-square for categorical variables, and logistic regression using the Wald chi-squared test; differences with p < 0.05 were considered to be stat

SUBMITTER: Silveira AM 

PROVIDER: S-EPMC10031372 | biostudies-literature | 2023 Mar-Apr

REPOSITORIES: biostudies-literature