Potential health and economic impact of paediatric vaccination using next-generation influenza vaccines in Kenya: a modelling study.

ABSTRACT:

Background

Influenza is a major year-round cause of respiratory illness in Kenya, particularly in children under 5. Current influenza vaccines result in short-term, strain-specific immunity and were found in a previous study not to be cost-effective in Kenya. However, next-generation vaccines are in development that may have a greater impact and cost-effectiveness profile.

Methods

We expanded a model previously used to evaluate the cost-effectiveness of seasonal influenza vaccines in Kenya to include next-generation vaccines by allowing for enhanced vaccine characteristics and multi-annual immunity. We specifically examined vaccinating children under 5 years of age with improved vaccines, evaluating vaccines with combinations of increased vaccine effectiveness, cross-protect

SUBMITTER: Waterlow NR 

PROVIDER: S-EPMC10032252 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature