Cross-sectional study to describe allergic rhinitis flare-ups and associated airways phenotype in house dust mite sensitization

ABSTRACT:

Objectives

To quantify and describe flare-ups of house dust mite allergic rhinitis (HDM-AR) which had occurred during the last 12 months in a population of adults and children candidate for Allergen ImmunoTherapy (AIT). Next, to identify associated clinical features.

Materials and methods

This was an observational, multicenter, cross-sectional study that included patients aged ≥ 5 years with HDM-AR eligible for AIT and without prior AIT for at least 12 months. Flare-ups were all period with impairment of quality of life (QoL) and requiring a change in their usual treatment. Data were collected using medical records and patient questionnaires. Variables associated with the occurrence of ≥ 2 AR flare-ups were identified.

Results

1,701 patients were included (averag

SUBMITTER: de Gabory L 

PROVIDER: S-EPMC10035855 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature