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The first genome assembly of the amphibian nematode parasite (Aplectana chamaeleonis).

ABSTRACT: Cosmocercoid nematodes are common parasites of the digestive tract of amphibians. Genomic resources are important for understanding the evolution of a species and the molecular mechanisms of parasite adaptation. So far, no genome resource of Cosmocercoid has been reported. In 2020, a massive Cosmocercoid infection was found in the small intestine of a toad, causing severe intestinal blockage. We morphologically identified this parasite as A. chamaeleonis. Here, we report the first A. chamaeleonis genome with a genome size of 1.04 Gb. The repeat content of this A. chamaeleonis genome is 72.45%, and the total length is 751 Mb. This resource is fundamental for understanding the evolution of Cosmocercoid and provides the molecular basis for Cosmocercoid infection and control.

SUBMITTER: Han L

PROVIDER: S-EPMC10043924 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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The first genome assembly of the amphibian nematode parasite (Aplectana chamaeleonis).

Han Lei L Liu Tianlu T He Fengping F Hou Zhijun Z

GigaByte (Hong Kong, China) 20230327

Cosmocercoid nematodes are common parasites of the digestive tract of amphibians. Genomic resources are important for understanding the evolution of a species and the molecular mechanisms of parasite adaptation. So far, no genome resource of Cosmocercoid has been reported. In 2020, a massive Cosmocercoid infection was found in the small intestine of a toad, causing severe intestinal blockage. We morphologically identified this parasite as A. chamaeleonis. Here, we report the first A. c ...[more]

PMID: 36999120

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