High-Throughput and Automated Detection of HLA-B*27 Using the LabTurbo^TM AIO System.

ABSTRACT: The adoption of an automated system can decrease the hands-on time requirements in a clinical laboratory setting. For the detection of HLA-B*27, implementing a high-throughput and fully automated system has several advantages over using manual methods. Therefore, this study aimed to evaluate automation efficiency for the detection of HLA-B*27. Peripheral blood samples were obtained from 50 participants, and DNA was isolated from these samples. A Pharmigene PG27 detection kit was used for the qualitative detection of HLA-B*27. The performances of the semi-automated and fully automated LabTurbo^TM AIO systems in the detection of HLA-B*27 were compared. The mean absorbance (optical density) values for the Maelstrom^TM 8 and LabTurbo^TM AIO systems were found to b

SUBMITTER: Chou YC 

PROVIDER: S-EPMC10046602 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature