Functional Enhancement of Guar Gum-Based Hydrogel by Polydopamine and Nanocellulose.

ABSTRACT: The development of green, biomedical hydrogels using natural polymers is of great significance. From this viewpoint, guar gum (GG) has been widely used for hydrogel preparation; however, its mechanical strength and adhesion often cannot satisfy the biomedical application. Therefore, in the present study, gelatin and a cellulose nanocrystal (CNC) were first applied to overcome the defects of guar gum hydrogel. Dopamine was self-polymerized into polydopamine (PDA) on the gelatin chain at alkaline condition, and gelatin-polydopamine (Gel-PDA) further cross-linked with guar gum and CNC via the borate-didiol bond, intramolecular Schiff base reaction, and Michael addition. CNC not only interacted with guar gum using borate chemistry but also acted as a mechanical reinforcer. The obtained Gel-PDA

SUBMITTER: Pak S 

PROVIDER: S-EPMC10048423 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature